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Tropomyosin movement is described by a quantitative high-resolution model of X-ray diffraction of contracting muscle

Contraction of skeletal and cardiac muscle is controlled by Ca2+ ions via regulatory proteins, troponin (Tn) and tropomyosin (Tpm) associated with the thin actin filaments in sarcomeres. In the absence of Ca2+, Tn-C binds actin and shifts the Tpm strand to a position where it blocks myosin binding t...

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Main Authors: Koubassova, Natalia A., Bershitsky, Sergey Y., Ferenczi, Michael Alan, Narayanan, Theyencheri, Tsaturyan, Andrey K.
其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
格式: Article
語言:English
出版: 2017
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在線閱讀:https://hdl.handle.net/10356/82598
http://hdl.handle.net/10220/42316
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