Precision oncology : oncogenic stat3 signalling in brain tumours

• 主要作者: Tan, Melanie Si Yan
• 其他作者: Tan Nguan Soon, Andrew
• 格式: Theses and Dissertations
• 語言: English
• 出版: 2019
• 主題: Science::Biological sciences::Human anatomy and physiology::Neurobiology; Science::Biological sciences::Molecular biology
• 在線閱讀: https://hdl.handle.net/10356/82741; http://hdl.handle.net/10220/49094
• 機構: Nanyang Technological University

Brain tumour patients diagnosed with grade IV glioblastoma often show dismal prognosis despite the standard of care chemo- and radiation therapies. The Cancer Genome Atlas effort demonstrated that transcriptomic profiles distinguish three glioma-intrinsic subtypes, each with unique genetic aberratio...