Elucidating the role of metabolic changes in modulating cell fate following treatment with anti-mitotic drugs

• المؤلف الرئيسي: Wong, Alex Xing Fah
• مؤلفون آخرون: Karen Crasta
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2019
• الموضوعات: DRNTU::Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/82972; http://hdl.handle.net/10220/47517
• المؤسسة: Nanyang Technological University

Anti-mitotic drugs are the most-commonly utilised class of chemotherapeutic agents that are administered as first-line therapy; however, their clinical success has been impeded by chemoresistance and disease relapse. Better understanding of the cellular pathways underlying this escape from antimitot...