Developmental analysis of bone marrow neutrophils reveals populations specialized in expansion, trafficking, and effector functions

• المؤلفون الرئيسيون: Kwok, Immanuel Weng Han, Leong, Penny Hweixian, Evrard, Maximilien, Chong, Shu Zhen, Teng, Karen W.W., Becht, Etienne, Chen, Jinmiao, Sieow, Je Lin, Ching, Goh Chi, Devi, Sapna, Adrover, José Maria, Li, Jackson L.Y., Liong, Ka Hang, Tan, Leonard, Poon, Zhiyong, Foo, Shihui, Chua, Jia Wang, Su, I-Hsin, Balabanian, Karl, Bachelerie, Françoise, Biswas, Subhra K., Larbi, Anis, Hwang, William Y.K., Madan, Vikas, Koeffler, H. Phillip, Wong, Siew Cheng, Newell, Evan W., Hidalgo, Andrés, Ginhoux, Florent, Ng, Lai Guan
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2019
• الموضوعات: Granulopoiesis; Trafficking; Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/83127; http://hdl.handle.net/10220/50413

Neutrophils are specialized innate cells that require constant replenishment from proliferative bone marrow (BM) precursors as a result of their short half-life. Although it is established that neutrophils are derived from the granulocyte-macrophage progenitor (GMP), the differentiation pathways fro...