Hydrogel effects rapid biofilm debridement with ex situ contact-kill to eliminate multidrug resistant bacteria in vivo

• Main Authors: Yeo, Chun Kiat, Vikhe, Yogesh Shankar, Li, Peng, Guo, Zanru, Greenberg, Peter, Duan, Hongwei, Tan, Nguan Soon, Chan-Park, Mary B.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Hydrogel; Antibacterial
• Online Access: https://hdl.handle.net/10356/83170; http://hdl.handle.net/10220/45047
• Institution: Nanyang Technological University

Multi-drug resistance and the refractory character of bacterial biofilms are among the most difficult challenges in infection treatment. Current antimicrobial strategies typically are much more effective for prevention of biofilm formation than for eradication of established biofilms; these strategi...