Implementation of machine learning and other simulation protocols for the representation of G-Quadruplex stabilizer
Human chromosomal telomeres are capable of forming G-Quadruplex structures, which can inhibit the activity of telomerase, an enzyme commonly found in cancerous cells and largely responsible for their immortality. The inhibition may therefore lead to cell apoptosis in these cancer cells. As such, the...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2019
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| Online Access: | https://hdl.handle.net/10356/83241 http://hdl.handle.net/10220/50085 |
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| Institution: | Nanyang Technological University |
| Language: | English |