Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects
Chromosomal instability (CIN), a higher propensity for loss or gain of whole chromosomes, is a hallmark of cancer and is associated with poor prognosis and drug resistance in multiple types of cancers. CIN often generates aneuploid, including polyploid, cells which contain abnormal number of chromos...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2019
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| Online Access: | https://hdl.handle.net/10356/83258 http://hdl.handle.net/10220/48003 |
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| Institution: | Nanyang Technological University |
| Language: | English |