Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects
Chromosomal instability (CIN), a higher propensity for loss or gain of whole chromosomes, is a hallmark of cancer and is associated with poor prognosis and drug resistance in multiple types of cancers. CIN often generates aneuploid, including polyploid, cells which contain abnormal number of chromos...
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Main Author: | He, Qianqian |
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Other Authors: | Karen Crasta |
Format: | Theses and Dissertations |
Language: | English |
Published: |
2019
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/83258 http://hdl.handle.net/10220/48003 |
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Institution: | Nanyang Technological University |
Language: | English |
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