Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer

Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer

A new drug concentration meter is developed. In vivo drug release can be monitored precisely via a self-indicating drug delivery system consisting of a new aggregation-induced emission thermoresponsive hydrogel. By taking the advantage of a self-indicating system, one can easily detect the depletion...

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Bibliographic Details
Main Authors: Liow, Sing Shy, Dou, Qingqing, Kai, Dan, Li, Zibiao, Sugiarto, Sigit, Yu, Chris Yee Yung, Kwok, Ryan Tsz Kin, Chen, Xiaohong, Wu, Yun-Long, Ong, Seow Theng, Kizhakeyil, Atish, Verma, Navin Kumar, Tang, Ben Zhong, Loh, Xian Jun
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2017
Subjects:
AIE micelles
Thermogels
Online Access:https://hdl.handle.net/10356/83614
http://hdl.handle.net/10220/42714
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Institution: Nanyang Technological University
Language: English
Description
Summary:A new drug concentration meter is developed. In vivo drug release can be monitored precisely via a self-indicating drug delivery system consisting of a new aggregation-induced emission thermoresponsive hydrogel. By taking the advantage of a self-indicating system, one can easily detect the depletion of drugs, and reinject to maintain a dosage in the optimal therapeutic window.

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