Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer
A new drug concentration meter is developed. In vivo drug release can be monitored precisely via a self-indicating drug delivery system consisting of a new aggregation-induced emission thermoresponsive hydrogel. By taking the advantage of a self-indicating system, one can easily detect the depletion...
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2017
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sg-ntu-dr.10356-836142020-11-01T05:18:50Z Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer Liow, Sing Shy Dou, Qingqing Kai, Dan Li, Zibiao Sugiarto, Sigit Yu, Chris Yee Yung Kwok, Ryan Tsz Kin Chen, Xiaohong Wu, Yun-Long Ong, Seow Theng Kizhakeyil, Atish Verma, Navin Kumar Tang, Ben Zhong Loh, Xian Jun Lee Kong Chian School of Medicine (LKCMedicine) AIE micelles Thermogels A new drug concentration meter is developed. In vivo drug release can be monitored precisely via a self-indicating drug delivery system consisting of a new aggregation-induced emission thermoresponsive hydrogel. By taking the advantage of a self-indicating system, one can easily detect the depletion of drugs, and reinject to maintain a dosage in the optimal therapeutic window. ASTAR (Agency for Sci., Tech. and Research, S’pore) MOE (Min. of Education, S’pore) Accepted version 2017-06-16T03:17:50Z 2019-12-06T15:26:46Z 2017-06-16T03:17:50Z 2019-12-06T15:26:46Z 2016 Journal Article Liow, S. S., Dou, Q., Kai, D., Li, Z., Sugiarto, S., Yu, C. Y. Y., et al. (2017). Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer. Small, 13(7), 1603404-. 1613-6810 https://hdl.handle.net/10356/83614 http://hdl.handle.net/10220/42714 10.1002/smll.201603404 en Small © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the author created version of a work that has been peer reviewed and accepted for publication by Small, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1002/smll.201603404]. 26 p. application/pdf |
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Nanyang Technological University |
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NTU Library |
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Asia |
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Singapore Singapore |
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| topic |
AIE micelles Thermogels |
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AIE micelles Thermogels Liow, Sing Shy Dou, Qingqing Kai, Dan Li, Zibiao Sugiarto, Sigit Yu, Chris Yee Yung Kwok, Ryan Tsz Kin Chen, Xiaohong Wu, Yun-Long Ong, Seow Theng Kizhakeyil, Atish Verma, Navin Kumar Tang, Ben Zhong Loh, Xian Jun Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer |
| description |
A new drug concentration meter is developed. In vivo drug release can be monitored precisely via a self-indicating drug delivery system consisting of a new aggregation-induced emission thermoresponsive hydrogel. By taking the advantage of a self-indicating system, one can easily detect the depletion of drugs, and reinject to maintain a dosage in the optimal therapeutic window. |
| author2 |
Lee Kong Chian School of Medicine (LKCMedicine) |
| author_facet |
Lee Kong Chian School of Medicine (LKCMedicine) Liow, Sing Shy Dou, Qingqing Kai, Dan Li, Zibiao Sugiarto, Sigit Yu, Chris Yee Yung Kwok, Ryan Tsz Kin Chen, Xiaohong Wu, Yun-Long Ong, Seow Theng Kizhakeyil, Atish Verma, Navin Kumar Tang, Ben Zhong Loh, Xian Jun |
| format |
Article |
| author |
Liow, Sing Shy Dou, Qingqing Kai, Dan Li, Zibiao Sugiarto, Sigit Yu, Chris Yee Yung Kwok, Ryan Tsz Kin Chen, Xiaohong Wu, Yun-Long Ong, Seow Theng Kizhakeyil, Atish Verma, Navin Kumar Tang, Ben Zhong Loh, Xian Jun |
| author_sort |
Liow, Sing Shy |
| title |
Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer |
| title_short |
Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer |
| title_full |
Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer |
| title_fullStr |
Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer |
| title_full_unstemmed |
Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer |
| title_sort |
long-term real-time in vivo drug release monitoring with aie thermogelling polymer |
| publishDate |
2017 |
| url |
https://hdl.handle.net/10356/83614 http://hdl.handle.net/10220/42714 |
| _version_ |
1683493563875196928 |