Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer

• Main Authors: Liow, Sing Shy, Dou, Qingqing, Kai, Dan, Li, Zibiao, Sugiarto, Sigit, Yu, Chris Yee Yung, Kwok, Ryan Tsz Kin, Chen, Xiaohong, Wu, Yun-Long, Ong, Seow Theng, Kizhakeyil, Atish, Verma, Navin Kumar, Tang, Ben Zhong, Loh, Xian Jun
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2017
• Subjects: AIE micelles; Thermogels
• Online Access: https://hdl.handle.net/10356/83614; http://hdl.handle.net/10220/42714
• Institution: Nanyang Technological University

A new drug concentration meter is developed. In vivo drug release can be monitored precisely via a self-indicating drug delivery system consisting of a new aggregation-induced emission thermoresponsive hydrogel. By taking the advantage of a self-indicating system, one can easily detect the depletion...