Mechanical unfolding kinetics of the SRV-1 gag-pro mRNA pseudoknot: possible implications for −1 ribosomal frameshifting stimulation

• المؤلفون الرئيسيون: Zhong, Zhensheng, Yang, Lixia, Zhang, Haiping, Shi, Jiahao, Vandana, J. Jeya, Lam, Do Thuy Uyen Ha, Olsthoorn, René C. L., Lu, Lanyuan, Chen, Gang
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2017
• الموضوعات: Biophysical chemistry; Molecular conformation
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/83910; http://hdl.handle.net/10220/42835

Minus-one ribosomal frameshifting is a translational recoding mechanism widely utilized by many RNA viruses to generate accurate ratios of structural and catalytic proteins. An RNA pseudoknot structure located in the overlapping region of the gag and pro genes of Simian Retrovirus type 1 (SRV-1) sti...