Mechanical unfolding kinetics of the SRV-1 gag-pro mRNA pseudoknot: possible implications for −1 ribosomal frameshifting stimulation

• Main Authors: Zhong, Zhensheng, Yang, Lixia, Zhang, Haiping, Shi, Jiahao, Vandana, J. Jeya, Lam, Do Thuy Uyen Ha, Olsthoorn, René C. L., Lu, Lanyuan, Chen, Gang
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2017
• 主題: Biophysical chemistry; Molecular conformation
• 在線閱讀: https://hdl.handle.net/10356/83910; http://hdl.handle.net/10220/42835

Minus-one ribosomal frameshifting is a translational recoding mechanism widely utilized by many RNA viruses to generate accurate ratios of structural and catalytic proteins. An RNA pseudoknot structure located in the overlapping region of the gag and pro genes of Simian Retrovirus type 1 (SRV-1) sti...