Exploring cancer stem cell niche directed tumor growth

• Main Authors: Sottoriva, Andrea., Sloot, Peter M. A., Medema, Jan Paul., Vermeulen, Louis.
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Computer science and engineering
• Online Access: https://hdl.handle.net/10356/84319; http://hdl.handle.net/10220/10174
• Institution: Nanyang Technological University

The finding that only a sub-fraction of tumor cells, so called Cancer Stem Cells (CSC), is endowed with the capacity to initiate new tumors has important consequences for fundamental as well as clinical cancer research. Previously we established by computational modeling techniques that CSC driven t...