Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity

Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity

The recently developed concept of cancer stem cells (CSC) sheds new light on various aspects of tumor growth and progression. Here, we present a mathematical model of malignancies to investigate how a hierarchical organized cancer cell population affects the fundamental properties of solid malignanc...

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Bibliographic Details
Main Authors: Sottoriva, Andrea, Verhoeff, Joost J. C., Borovski, Tijana, McWeeney, Shannon, Naumov, Lev, Medema, Jan Paul, Sloot, Peter M. A., Vermeulen, Louis
Other Authors: School of Computer Engineering
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/96024
http://hdl.handle.net/10220/10119
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/96024
http://hdl.handle.net/10220/10119

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