Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity
The recently developed concept of cancer stem cells (CSC) sheds new light on various aspects of tumor growth and progression. Here, we present a mathematical model of malignancies to investigate how a hierarchical organized cancer cell population affects the fundamental properties of solid malignanc...
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Main Authors: | Sottoriva, Andrea, Verhoeff, Joost J. C., Borovski, Tijana, McWeeney, Shannon, Naumov, Lev, Medema, Jan Paul, Sloot, Peter M. A., Vermeulen, Louis |
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Other Authors: | School of Computer Engineering |
Format: | Article |
Language: | English |
Published: |
2013
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Online Access: | https://hdl.handle.net/10356/96024 http://hdl.handle.net/10220/10119 |
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Institution: | Nanyang Technological University |
Language: | English |
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