Recent advances in chitosan-based carriers for gene delivery

• Main Authors: Cao, Ye, Tan, Yang Fei, Wong, Yee Shan, Liew, Melvin Wen Jie, Venkatraman, Subbu
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: Engineering::Materials; Chitosan; siRNA
• Online Access: https://hdl.handle.net/10356/84441; http://hdl.handle.net/10220/49788
• Institution: Nanyang Technological University

Approximately 4000 diseases are associated with malfunctioning genes in a particular cell type. Gene-based therapy provides a platform to modify the disease-causing genes expression at the cellular level to treat pathological conditions. However, gene delivery is challenging as these therapeutic gen...