A supersaturating delivery system of silibinin exhibiting high payload achieved by amorphous nano-complexation with chitosan

The therapeutic potentials of silibinin – a phytochemical isolated from milk thistle plants – have not been fully realized due to its poor oral bioavailability caused by the low aqueous solubility. Existing solubility enhancement strategies of silibinin by nanonization were limited by their low payl...

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Bibliographic Details
Main Authors: Nguyen, Minh-Hiep, Yu, Hong, Dong, Bingxue, Hadinoto, Kunn
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/84608
http://hdl.handle.net/10220/41896
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Institution: Nanyang Technological University
Language: English
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