The rapid in vivo evolution of Pseudomonas aeruginosa in ventilator-associated pneumonia patients leads to attenuated virulence

Pseudomonas aeruginosa is an opportunistic pathogen that causes severe airway infections in humans. These infections are usually difficult to treat and associated with high mortality rates. While colonizing the human airways, P. aeruginosa could accumulate genetic mutations that often lead to its be...

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Main Authors: Wang, Ke, Chen, Yi-qiang, Salido, May M., Kohli, Gurjeet S., Kong, Jin-liang, Liang, Hong-jie, Yao, Zi-ting, Xie, Yan-tong, Wu, Hua-yu, Cai, Shuang-qi, Drautz-Moses, Daniela I., Darling, Aaron E., Schuster, Stephan C., Yang, Liang, Ding, Yichen
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/85357
http://hdl.handle.net/10220/48202
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Institution: Nanyang Technological University
Language: English