Chikungunya virus nsP4 RNA-dependent RNA polymerase core domain displays detergent-sensitive primer extension and terminal adenylyltransferase activities
Chikungunya virus (CHIKV) is an important arboviral infectious agent in tropical and subtropical regions, often causing persistent and debilitating disease. The viral enzyme non-structural protein 4 (nsP4), as RNA-dependent RNA polymerase (RdRP), catalyzes the formation of negative-sense, genomic an...
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Main Authors: | Chen, Ming Wei, Tan, Yaw Bia, Zheng, Jie, Zhao, Yongqian, Lim, Bee Ting, Cornvik, Tobias, Lescar, Julien, Ng, Lisa Fong Poh, Luo, Dahai |
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Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2017
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/86660 http://hdl.handle.net/10220/44135 |
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Institution: | Nanyang Technological University |
Language: | English |
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