Structure of the competence pilus major pilin ComGC in Streptococcus pneumoniae

• Main Authors: Muschiol, Sandra, Erlendsson, Simon, Aschtgen, Marie-Stephanie, Oliveira, Vitor, Schmieder, Peter, De Lichtenberg, Casper, Teilum, Kaare, Boesen, Thomas, Akbey, Umit, Henriques-Normark, Birgitta
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: Hydrophobic Patch; Biofilm Formation
• Online Access: https://hdl.handle.net/10356/87253; http://hdl.handle.net/10220/44346
• Institution: Nanyang Technological University

Type IV pili are important virulence factors on the surface of many pathogenic bacteria and have been implicated in a wide range of diverse functions, including attachment, twitching motility, biofilm formation, and horizontal gene transfer. The respiratory pathogen Streptococcus pneumoniae deploys...