N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5

N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5

N6-Methyladenosine (m6A) is currently one of the most intensively studied post-transcriptional modifications in RNA. Due to its critical role in epigenetics and physiological links to several human diseases, it is also of tremendous biological and medical interest. The m6A mark is dynamically revers...

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Bibliographic Details
Main Authors: Zou, Shui, Toh, Joel D. W., Wong, Kendra H. Q., Gao, Yong-Gui, Hong, Wanjin, Woon, Esther C. Y.
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Protein Conformation
Demethylation
DRNTU::Science::Biological sciences
Online Access:https://hdl.handle.net/10356/87480
http://hdl.handle.net/10220/46698
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/87480
http://hdl.handle.net/10220/46698

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