N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5
N6-Methyladenosine (m6A) is currently one of the most intensively studied post-transcriptional modifications in RNA. Due to its critical role in epigenetics and physiological links to several human diseases, it is also of tremendous biological and medical interest. The m6A mark is dynamically revers...
Saved in:
Main Authors: | Zou, Shui, Toh, Joel D. W., Wong, Kendra H. Q., Gao, Yong-Gui, Hong, Wanjin, Woon, Esther C. Y. |
---|---|
Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2018
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/87480 http://hdl.handle.net/10220/46698 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
Similar Items
-
N 6 -Methyladenosine: A conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5
by: Zou, S, et al.
Published: (2020) -
A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N6-methyladenosine demethylase FTO
by: Toh, Joel D. W., et al.
Published: (2015) -
A fluorescent methylation-switchable probe for highly sensitive analysis of FTO N6-methyladenosine demethylase activity in cells
by: Cheong, A., et al.
Published: (2022) -
STRUCTURAL AND MECHANISTIC STUDIES OF NUCLEIC ACID DEMETHYLASE FTO
by: TOH DEWEI JOEL
Published: (2017) -
STUDIES TOWARDS THE DEVELOPMENT OF HIGHLY SELECTIVE EPIGENETIC SMALL MOLECULE PROBES FOR THE ALKB FAMILY OF NUCLIEIC ACID DEMETHYLASES
by: MOHUA DAS
Published: (2020)