Structural and functional characterization of flavivirus non-structural protein 3 (NS3) in solution and atomic and enzymatic insights of vancomysin resistant enterococcus faecalis (V583) alkyl hydroperoxide subunit C

• المؤلف الرئيسي: Pan, Ankita
• مؤلفون آخرون: Gerhard Gruber
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2018
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/87918; http://hdl.handle.net/10220/45578

This thesis focuses on the non-structural protein 3 (NS3) of two flaviviral pathogens, the Dengue (DENV; DENV-2) and Zika virus (ZIKV), that have emerged as a major health concern in Singapore and world-wide. The NS3 comprises of an N-terminal serine protease domain and a C-terminal helicase domain...