A Biodegradable, Sustained-Released, Tacrolimus Microfilm Drug Delivery System for the Management of Allergic Conjunctivitis in a Mouse Model

• Main Authors: Liu, Yu-Chi, Ng, Xu Wen, Teo, Ericia Pei Wen, Ang, Heng-Pei, Lwin, Nyein Chan, Chan, Nicole Shu Wen, Venkatraman, Subbu S., Wong, Tina Tzeeling, Mehta, Jodhbir Singh
• 其他作者: School of Materials Science & Engineering
• 格式: Article
• 語言: English
• 出版: 2018
• 主題: Allergic Conjunctivitis; Tacrolimus
• 在線閱讀: https://hdl.handle.net/10356/88206; http://hdl.handle.net/10220/44577

Purpose: To investigate the drug release profiles of a tacrolimus-loaded poly(D,L-lactide-co-ε-caprolactone) (PLC) microfilm, and to evaluate its efficacy on the treatment of allergic conjunctivitis using a mouse model. Methods: The in vitro and in vivo drug release profiles were first characteri...