A biodegradable, sustained-released, prednisolone acetate microfilm drug delivery system effectively prolongs corneal allograft survival in the rat keratoplasty model

• Main Authors: Liu, Yu-Chi, Peng, Yan, Lwin, Nyein Chan, Venkatraman, Subbu S., Wong, Tina T., Mehta, Jodhbir S.
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/97672; http://hdl.handle.net/10220/13228
• Institution: Nanyang Technological University

Frequent and long-term use of topical corticosteroids after corneal transplantation is necessary to prevent graft rejection. However, it relies heavily on patient compliance, and sustained therapeutic drug levels are often not achieved with administration of topical eye drops. A biodegradable drug d...