Evaluation of a Sustained-release Prednisolone Acetate Biodegradable Subconjunctival Implant in a Non-Human Primate Model

Evaluation of a Sustained-release Prednisolone Acetate Biodegradable Subconjunctival Implant in a Non-Human Primate Model

Purpose: We evaluate the toxicity and plasma toxicokinetic (TK) profile of a biodegradable subconjunctival microrod for sustained prednisolone acetate (PA) release over 12 weeks in a non-human primate model. Methods: The biodegradable copolymer poly(l-lactide-co-ε-caprolactone) (PLC) and 40-wt% PA m...

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Bibliographic Details
Main Authors: Liu, Yu-Chi, Ng, Anthony Herr Cheun, Ng, Xu Wen, Yan, Peng, Venkatraman, Subbu Subramanian, Mehta, Jodhbir Singh, Wong, Tina Tzee Ling
Other Authors: School of Materials Science & Engineering
Format: Article
Language:English
Published: 2018
Subjects:
Drug Delivery
Subconjunctival
Online Access:https://hdl.handle.net/10356/88205
http://hdl.handle.net/10220/44578
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/88205
http://hdl.handle.net/10220/44578

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