Evaluation of a Sustained-release Prednisolone Acetate Biodegradable Subconjunctival Implant in a Non-Human Primate Model
Purpose: We evaluate the toxicity and plasma toxicokinetic (TK) profile of a biodegradable subconjunctival microrod for sustained prednisolone acetate (PA) release over 12 weeks in a non-human primate model. Methods: The biodegradable copolymer poly(l-lactide-co-ε-caprolactone) (PLC) and 40-wt% PA m...
Saved in:
Main Authors: | Liu, Yu-Chi, Ng, Anthony Herr Cheun, Ng, Xu Wen, Yan, Peng, Venkatraman, Subbu Subramanian, Mehta, Jodhbir Singh, Wong, Tina Tzee Ling |
---|---|
Other Authors: | School of Materials Science & Engineering |
Format: | Article |
Language: | English |
Published: |
2018
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/88205 http://hdl.handle.net/10220/44578 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
Patient acceptance and attitude toward an alternative method of subconjunctival injection for the medical treatment of glaucoma
by: Chong, R.S., et al.
Published: (2016) -
Evaluation of a prednisolone acetate-loaded subconjunctival implant for the treatment of recurrent uveitis in a rabbit model
by: Ang, Marcus, et al.
Published: (2014) -
Evaluation of a prednisolone acetate-loaded subconjunctival implant for the treatment of recurrent uveitis in a rabbit model
by: Ang M., et al.
Published: (2019) -
Biocompatibility and biodegradation studies of subconjunctival implants in rabbit eyes
by: Peng Y., et al.
Published: (2019) -
A biodegradable, sustained-released, prednisolone acetate microfilm drug delivery system effectively prolongs corneal allograft survival in the rat keratoplasty model
by: Liu, Yu-Chi, et al.
Published: (2013)