Single-cell transcriptomics of East-Asian pancreatic islets cells

• Main Authors: Tay, Vanessa Shi Yun, Boehm, Bernhard Otto, Dorajoo, Rajkumar, Ali, Yusuf, Kang, Jonathan, Samydurai, Sudhagar, Liu, Jianjun
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: Gene Expression; Islet Cell; DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/88280; http://hdl.handle.net/10220/45671
• Institution: Nanyang Technological University

Single-cell RNA-seq (scRNA-seq) of pancreatic islets have reported on α- and β-cell gene expression in mice and subjects of predominantly European ancestry. We aimed to assess these findings in East-Asian islet-cells. 448 islet-cells were captured from three East-Asian non-diabetic subjects for scRN...