A ratiometric fluorescent molecular probe with enhanced two-photon response upon Zn 2+ binding for in vitro and in vivo bioimaging

• Main Authors: Divya, Kizhmuri P., Sreejith, Sivaramapanicker, Ashokkumar, Pichandi, Kang, Yuzhan, Peng, Qiwen, Maji, Swarup Kumar, Yan, Tong, Yu, Hanry, Zhao, Yanli, Ramamurthy, Perumal, Ajayaghosh, Ayyappanpillai
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: DRNTU::Science::Chemistry; Molecular Probes; Fluorescence
• Online Access: https://hdl.handle.net/10356/88298; http://hdl.handle.net/10220/45703
• Institution: Nanyang Technological University

A bipyridine centered donor–acceptor–donor (D–π–A–π–D) type ratiometric fluorescent molecular probe exhibited an unprecedented enhancement in the two-photon absorption (2PA) cross section upon Zn2+ binding. Moreover, owing to the excited state charge-transfer of the fluorophore π-backbone, a signifi...