An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias

• Main Authors: Datta, Arnab, Chai, Yuek Ling, Tan, Jing Min, Lee, Jasinda H., Francis, Paul T., Chen, Christopher P., Sze, Siu Kwan, Lai, Mitchell K. P.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Dementia With Lewy Bodies; Lewy Body Dementias; DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/88540; http://hdl.handle.net/10220/45822
• Institution: Nanyang Technological University

Lewy body dementias are the second most common cause of neurodegenerative dementia in the elderly after Alzheimer’s disease (AD). The two clinical subgroups of Lewy body dementias, namely, dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD), are differentiated by the chronology of...