The Drosophila Dicer-1 partner loquacious enhances miRNA processing from hairpins with unstable structures at the dicing site

The Drosophila Dicer-1 partner loquacious enhances miRNA processing from hairpins with unstable structures at the dicing site

In Drosophila, Dicer-1 binds Loquacious-PB (Loqs-PB) as its major co-factor. Previous analyses indicated that loqs mutants only partially impede miRNA processing, but the activity of minor isoforms or maternally deposited Loqs was not eliminated in these studies. We addressed this by generating a ce...

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Bibliographic Details
Main Authors: Lim, Mandy Yu Theng, Ng, Alvin Wei Tian, Chou, Yuting, Lim, Teck Por, Simcox, Amanda, Tucker-Kellogg, Greg, Okamura, Katsutomo
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Drosophila Proteins
RNA Processing
DRNTU::Science::Biological sciences
Online Access:https://hdl.handle.net/10356/88607
http://hdl.handle.net/10220/46946
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/88607
http://hdl.handle.net/10220/46946

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