Proinflammatory cytokines induce endocrine differentiation in pancreatic ductal cells via STAT3-dependent NGN3 activation
A major goal of diabetes research is to develop strategies that replenish pancreatic insulin-producing beta cells. One emerging strategy is to harness pancreatic plasticity—the ability of pancreatic cells to undergo cellular interconversions—a phenomenon implicated in physiological stress and pancre...
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Main Authors: | Valdez, Ivan Achel, Dirice, Ercument, Gupta, Manoj K., Shirakawa, Jun, Teo, Adrian Kee Keong, Kulkarni, Rohit N. |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2018
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/88611 http://hdl.handle.net/10220/46945 |
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Institution: | Nanyang Technological University |
Language: | English |
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