A mechanism underlying position-specific regulation of alternative splicing

Many RNA-binding proteins including a master regulator of splicing in developing brain and muscle, polypyrimidine tract-binding protein 1 (PTBP1), can either activate or repress alternative exons depending on the pre-mRNA recruitment position. When bound upstream or within regulated exons PTBP1 tend...

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Bibliographic Details
Main Authors: Hamid, Fursham M., Makeyev, Eugene V.
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/88632
http://hdl.handle.net/10220/44671
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Institution: Nanyang Technological University
Language: English
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