Comparative transcriptomic and metagenomic analyses of influenza virus-infected nasal epithelial cells from multiple individuals reveal specific nasal-initiated signatures

• Main Authors: Tan, Kai Sen, Yan, Yan, Koh, Wai Ling Hiromi, Li, Liang, Choi, Hyungwon, Tran, Thai, Sugrue, Richard, Wang, De Yun, Chow, Vincent T.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Influenza; Transcriptomics; DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/88755; http://hdl.handle.net/10220/46976
• Institution: Nanyang Technological University

In vitro and in vivo research based on cell lines and animals are likely to be insufficient in elucidating authentic biological and physiological phenomena mimicking human systems, especially for generating pre-clinical data on targets and biomarkers. There is an obvious need for a model that can fu...