SynLethDB : synthetic lethality database toward discovery of selective and sensitive anticancer drug targets

Synthetic lethality (SL) is a type of genetic interaction between two genes such that simultaneous perturbations of the two genes result in cell death or a dramatic decrease of cell viability, while a perturbation of either gene alone is not lethal. SL reflects the biologically endogenous difference...

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Bibliographic Details
Main Authors: Guo, Jing, Liu, Hui, Zheng, Jie
Other Authors: School of Computer Science and Engineering
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/88975
http://hdl.handle.net/10220/46043
https://doi.org/10.21979/N9/CVEVDZ
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Institution: Nanyang Technological University
Language: English

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