Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5

• Main Authors: Shi, Meng, Chen, Bing, Mahajan, Divyanshu, Boh, Boon Kim, Zhou, Yan, Dutta, Bamaprasad, Tie, Hieng Chiong, Sze, Siu Kwan, Wu, Geng, Lu, Lei
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2019
• Subjects: Ragulator; DRNTU::Science::Biological sciences; Small GTPase
• Online Access: https://hdl.handle.net/10356/89116; http://hdl.handle.net/10220/47665
• Institution: Nanyang Technological University

The endosome-to-Golgi or endocytic retrograde trafficking pathway is an important post-Golgi recycling route. Here we show that amino acids (AAs) can stimulate the retrograde trafficking and regulate the cell surface localization of certain Golgi membrane proteins. By testing components of the AA-st...