Carbon–carbon bond activation of cyclobutenones enabled by the addition of chiral organocatalyst to ketone

• Main Authors: Li, Bao-Sheng, Wang, Yuhuang, Jin, Zhichao, Zheng, Pengcheng, Ganguly, Rakesh, Chi, Robin Yonggui
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Chemical Bonding; Organic Chemistry; DRNTU::Science::Chemistry
• Online Access: https://hdl.handle.net/10356/89159; http://hdl.handle.net/10220/46119
• Institution: Nanyang Technological University

The activation of carbon–carbon (C–C) bonds is an effective strategy in building functional molecules. The C–C bond activation is typically accomplished via metal catalysis, with which high levels of enantioselectivity are difficult to achieve due to high reactivity of metal catalysts and the metal-...