Topical delivery of senicapoc nanoliposomal formulation for ocular surface treatments

• Main Authors: Phua, Jie Liang, Hou, Aihua, Lui, Yuan Siang, Bose, Tanima, Chandy, George Kanianthara, Tong, Louis, Venkatraman, Subbu, Huang, Yingying
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Liposomes; Senicapoc; DRNTU::Engineering::Materials
• Online Access: https://hdl.handle.net/10356/89682; http://hdl.handle.net/10220/46325
• Institution: Nanyang Technological University

Topical ophthalmologic treatments have been facing great challenges with main limitations of low drug bioavailability, due to highly integrative defense mechanisms of the eye. This study rationally devised strategies to increase drug bioavailability by increasing ocular surface residence time of dru...