Cyclooxygenase-2 selectively controls renal blood flow through a novel pparβ/δ-dependent vasodilator pathway

Cyclooxygenase-2 selectively controls renal blood flow through a novel pparβ/δ-dependent vasodilator pathway

Cyclooxygenase-2 (COX-2) is an inducible enzyme expressed in inflammation and cancer targeted by nonsteroidal anti-inflammatory drugs. COX-2 is also expressed constitutively in discreet locations where its inhibition drives gastrointestinal and cardiovascular/renal side effects. Constitutive COX-2 e...

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Bibliographic Details
Main Authors: Shala, Fisnik, Nair, Anitha S., Ahmetaj-Shala, Blerina, Jiao, Jing, Kirkby, Nicholas S., Sampaio, Walkyria, Etelvino, Gisele, Alves, Daniele T., Anders, Katie L., Temponi, Rafael, Herschman, Harvey R., Wang, Xiaomeng, Wahli, Walter, Santos, Robson A., Mitchell, Jane A.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2018
Subjects:
Endothelium
Cyclooxygenase 2
DRNTU::Science::Medicine
Online Access:https://hdl.handle.net/10356/89772
http://hdl.handle.net/10220/46357
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/89772
http://hdl.handle.net/10220/46357

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