Cyclooxygenase-2 selectively controls renal blood flow through a novel pparβ/δ-dependent vasodilator pathway
Cyclooxygenase-2 (COX-2) is an inducible enzyme expressed in inflammation and cancer targeted by nonsteroidal anti-inflammatory drugs. COX-2 is also expressed constitutively in discreet locations where its inhibition drives gastrointestinal and cardiovascular/renal side effects. Constitutive COX-2 e...
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Main Authors: | Shala, Fisnik, Nair, Anitha S., Ahmetaj-Shala, Blerina, Jiao, Jing, Kirkby, Nicholas S., Sampaio, Walkyria, Etelvino, Gisele, Alves, Daniele T., Anders, Katie L., Temponi, Rafael, Herschman, Harvey R., Wang, Xiaomeng, Wahli, Walter, Santos, Robson A., Mitchell, Jane A. |
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Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2018
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/89772 http://hdl.handle.net/10220/46357 |
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Institution: | Nanyang Technological University |
Language: | English |
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