In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics

• Main Authors: Ai, Xiangzhao, Ho, Chris Jun Hui, Aw, Junxin, Attia, Amalina Binte Ebrahim, Mu, Jing, Wang, Yu, Wang, Xiaoyong, Wang, Yong, Liu, Xiaogang, Chen, Huabing, Gao, Mingyuan, Chen, Xiaoyuan, Yeow, Edwin Kok Lee, Liu, Gang, Olivo, Malini, Xing, Bengang
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Biomaterials; Drug Delivery; DRNTU::Science::Physics
• Online Access: https://hdl.handle.net/10356/89956; http://hdl.handle.net/10220/47167
• Institution: Nanyang Technological University

The development of precision nanomedicines to direct nanostructure-based reagents into tumour-targeted areas remains a critical challenge in clinics. Chemical reaction-mediated localization in response to tumour environmental perturbations offers promising opportunities for rational design of effect...