Scandium as a pre-catalyst for the deoxygenative allylation of benzylic alcohols

• Main Authors: Šolić, Ivan, Seankongsuk, Pattarakiat, Loh, Joanna Kejun, Vilaivan, Tirayut, Bates, Roderick Wayland
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2019
• Subjects: DRNTU::Science::Chemistry; Allylation; Benzylic Alcohols
• Online Access: https://hdl.handle.net/10356/90299; http://hdl.handle.net/10220/48477
• Institution: Nanyang Technological University

Scandium triflate is an effective pre-catalyst for the deoxygenative allylation of benzylic alcohols with a narrow substrate window. The reaction is shown to proceed through a “hidden Brønsted acid” mechanism. The reaction is efficient provided that the aryl group is neither too electron rich nor to...