Darkness in the human gene and protein function space : widely modest or absent illumination by the life science literature and the trend for fewer protein function discoveries since 2000

• Main Authors: Sinha, Swati, Eisenhaber, Birgit, Jensen, Lars Juhl, Kalbuaji, Bharata, Eisenhaber, Frank
• Other Authors: School of Computer Science and Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: Complete Human Genome; Gene Function Discovery; Engineering::Computer science and engineering
• Online Access: https://hdl.handle.net/10356/90338; http://hdl.handle.net/10220/49910
• Institution: Nanyang Technological University

The mentioning of gene names in the body of the scientific literature 1901–2017 and their fractional counting is used as a proxy to assess the level of biological function discovery. A literature score of one has been defined as full publication equivalent (FPE), the amount of literature necessary t...