Highly Fluorescent and Photostable Polymeric Nanofibers as Scaffolds for Cell Interfacing and Long-Term Tracking

Highly Fluorescent and Photostable Polymeric Nanofibers as Scaffolds for Cell Interfacing and Long-Term Tracking

Highly fluorescent polymeric nanofibers fabricated via electrospinning of PCL-DPP-PCL (photostable polycaprolactones–di(thiophene-2-yl)-diketopyrrolopyrrole–photostable polycaprolactones) and commercial PCL mixture show superior photostability and cytocompatibility for long-term tracking of cell–sub...

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Bibliographic Details
Main Authors: Diao, Hua Jia, Wang, Kai, Long, Hong Yan, Wang, Mingfeng, Chew, Sing Yian
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2016
Subjects:
Electrospinning
Oligodendrocytes
Online Access:https://hdl.handle.net/10356/93139
http://hdl.handle.net/10220/40999
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Institution: Nanyang Technological University
Language: English
Description
Summary:Highly fluorescent polymeric nanofibers fabricated via electrospinning of PCL-DPP-PCL (photostable polycaprolactones–di(thiophene-2-yl)-diketopyrrolopyrrole–photostable polycaprolactones) and commercial PCL mixture show superior photostability and cytocompatibility for long-term tracking of cell–substrate interaction. As a proof of concept, these PCL-DPP-PCL nanofibers enable clear visualization of intricate cell–substrate interactions such as oligodendrocyte myelination.

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