The transcription factor TFIIS zinc ribbon dipeptide Asp-Glu is critical for stimulation of elongation and RNA cleavage by RNA polymerase II

The eukaryotic transcription factor TFIIS enhances elongation and nascent transcript cleavage activities of RNA polymerase II in a stalled elongation complex. By site-directed mutagenesis, we have demonstrated that invariant residues Asp-261 and Glu-262 of the nucleic acid-binding TFIIS Zn ribbon ar...

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Bibliographic Details
Main Authors: Jeon, Choon Ju, Yoon, Ho Sup, Agarwal, Kan
Other Authors: School of Biological Sciences
Format: Conference or Workshop Item
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/94050
http://hdl.handle.net/10220/7484
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Institution: Nanyang Technological University
Language: English