Exploring the energy landscape of nucleic acid hairpins using laser temperature-jump and microfluidic mixing

Exploring the energy landscape of nucleic acid hairpins using laser temperature-jump and microfluidic mixing

We have investigated the multidimensionality of the free energy landscape accessible to a nucleic acid hairpin by measuring the relaxation kinetics in response to two very different perturbations of the folding/unfolding equilibrium, either a laser temperature-jump or ion-jump (from rapid mixing wit...

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Bibliographic Details
Main Authors: Kuznetsov, Serguei V., Lapidus, Lisa J., Narayanan, Ranjani, Zhu, Li, Velmurugu, Yogambigai, Roca, Jorjethe, Prehna, Gerd, Ansari, Anjum
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/95816
http://hdl.handle.net/10220/11261
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/95816
http://hdl.handle.net/10220/11261

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