Exploring the energy landscape of nucleic acid hairpins using laser temperature-jump and microfluidic mixing
We have investigated the multidimensionality of the free energy landscape accessible to a nucleic acid hairpin by measuring the relaxation kinetics in response to two very different perturbations of the folding/unfolding equilibrium, either a laser temperature-jump or ion-jump (from rapid mixing wit...
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| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://hdl.handle.net/10356/95816 http://hdl.handle.net/10220/11261 |
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| Institution: | Nanyang Technological University |
| Language: | English |