Tachyon search speeds up retrieval of similar sequences by several orders of magnitude

Summary: The usage of current sequence search tools becomes increasingly slower as databases of protein sequences continue to grow exponentially. Tachyon, a new algorithm that identifies closely related protein sequences ~200 times faster than standard BLAST, circumvents this limitation with a reduc...

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Main Authors: Sirota, Fernanda L., Sherman, Westley A., Tan, Joshua, Kuchibhatla, Durga, Gattermayer, Tobias, Kwoh, Chia Yee, Eisenhaber, Frank, Schneider, Georg, Maurer-Stroh, Sebastian
Other Authors: School of Computer Engineering
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/95996
http://hdl.handle.net/10220/10780
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-959962022-02-16T16:30:47Z Tachyon search speeds up retrieval of similar sequences by several orders of magnitude Sirota, Fernanda L. Sherman, Westley A. Tan, Joshua Kuchibhatla, Durga Gattermayer, Tobias Kwoh, Chia Yee Eisenhaber, Frank Schneider, Georg Maurer-Stroh, Sebastian School of Computer Engineering School of Biological Sciences Summary: The usage of current sequence search tools becomes increasingly slower as databases of protein sequences continue to grow exponentially. Tachyon, a new algorithm that identifies closely related protein sequences ~200 times faster than standard BLAST, circumvents this limitation with a reduced database and oligopeptide matching heuristic. 2013-06-27T03:34:55Z 2019-12-06T19:24:08Z 2013-06-27T03:34:55Z 2019-12-06T19:24:08Z 2012 2012 Journal Article Tan, J., Kuchibhatla, D., Sirota, F. L., Sherman, W. A., Gattermayer, T., Kwoh, C. Y., et al. (2012). Tachyon search speeds up retrieval of similar sequences by several orders of magnitude. Bioinformatics, 28(12), 1645-1646. 1367-4803 https://hdl.handle.net/10356/95996 http://hdl.handle.net/10220/10780 10.1093/bioinformatics/bts197 22531216 en Bioinformatics © 2012 The Author(s).
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
description Summary: The usage of current sequence search tools becomes increasingly slower as databases of protein sequences continue to grow exponentially. Tachyon, a new algorithm that identifies closely related protein sequences ~200 times faster than standard BLAST, circumvents this limitation with a reduced database and oligopeptide matching heuristic.
author2 School of Computer Engineering
author_facet School of Computer Engineering
Sirota, Fernanda L.
Sherman, Westley A.
Tan, Joshua
Kuchibhatla, Durga
Gattermayer, Tobias
Kwoh, Chia Yee
Eisenhaber, Frank
Schneider, Georg
Maurer-Stroh, Sebastian
format Article
author Sirota, Fernanda L.
Sherman, Westley A.
Tan, Joshua
Kuchibhatla, Durga
Gattermayer, Tobias
Kwoh, Chia Yee
Eisenhaber, Frank
Schneider, Georg
Maurer-Stroh, Sebastian
spellingShingle Sirota, Fernanda L.
Sherman, Westley A.
Tan, Joshua
Kuchibhatla, Durga
Gattermayer, Tobias
Kwoh, Chia Yee
Eisenhaber, Frank
Schneider, Georg
Maurer-Stroh, Sebastian
Tachyon search speeds up retrieval of similar sequences by several orders of magnitude
author_sort Sirota, Fernanda L.
title Tachyon search speeds up retrieval of similar sequences by several orders of magnitude
title_short Tachyon search speeds up retrieval of similar sequences by several orders of magnitude
title_full Tachyon search speeds up retrieval of similar sequences by several orders of magnitude
title_fullStr Tachyon search speeds up retrieval of similar sequences by several orders of magnitude
title_full_unstemmed Tachyon search speeds up retrieval of similar sequences by several orders of magnitude
title_sort tachyon search speeds up retrieval of similar sequences by several orders of magnitude
publishDate 2013
url https://hdl.handle.net/10356/95996
http://hdl.handle.net/10220/10780
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