Catalytic enantioselective conjugate addition of grignard reagents to cyclic enones using C 1 -1,1′-bisisoquinoline-based chiral ligands
New highly constrained chiral C1-1,10-bisisoquinoline ligands were examined in the enantioselective conjugate addition of Grignard reagents to cyclohexenone and cyclopentenone. The desired 1,4-adducts were obtained in excellent yield and moderate enantiomeric excess (up to 35%).
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sg-ntu-dr.10356-961442020-03-07T11:35:30Z Catalytic enantioselective conjugate addition of grignard reagents to cyclic enones using C 1 -1,1′-bisisoquinoline-based chiral ligands Judeh, Zaher M. A. Qi, Gao School of Chemical and Biomedical Engineering New highly constrained chiral C1-1,10-bisisoquinoline ligands were examined in the enantioselective conjugate addition of Grignard reagents to cyclohexenone and cyclopentenone. The desired 1,4-adducts were obtained in excellent yield and moderate enantiomeric excess (up to 35%). 2013-07-17T07:26:43Z 2019-12-06T19:26:18Z 2013-07-17T07:26:43Z 2019-12-06T19:26:18Z 2012 2012 Journal Article Qi, G., & Judeh, Z. M. A. (2012). Catalytic Enantioselective Conjugate Addition of Grignard Reagents to Cyclic Enones Using C 1 -1,1′-Bisisoquinoline-Based Chiral Ligands. Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry, 42(11), 1585-1592. https://hdl.handle.net/10356/96144 http://hdl.handle.net/10220/11770 10.1080/00397911.2010.541969 en Synthetic communications: an international journal for rapid communication of synthetic organic chemistry © 2012 Taylor & Francis Group, LLC. |
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Nanyang Technological University |
| building |
NTU Library |
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Singapore |
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| language |
English |
| description |
New highly constrained chiral C1-1,10-bisisoquinoline ligands were examined in the
enantioselective conjugate addition of Grignard reagents to cyclohexenone and cyclopentenone.
The desired 1,4-adducts were obtained in excellent yield and moderate enantiomeric
excess (up to 35%). |
| author2 |
School of Chemical and Biomedical Engineering |
| author_facet |
School of Chemical and Biomedical Engineering Judeh, Zaher M. A. Qi, Gao |
| format |
Article |
| author |
Judeh, Zaher M. A. Qi, Gao |
| spellingShingle |
Judeh, Zaher M. A. Qi, Gao Catalytic enantioselective conjugate addition of grignard reagents to cyclic enones using C 1 -1,1′-bisisoquinoline-based chiral ligands |
| author_sort |
Judeh, Zaher M. A. |
| title |
Catalytic enantioselective conjugate addition of grignard reagents to cyclic enones using
C
1
-1,1′-bisisoquinoline-based chiral ligands |
| title_short |
Catalytic enantioselective conjugate addition of grignard reagents to cyclic enones using
C
1
-1,1′-bisisoquinoline-based chiral ligands |
| title_full |
Catalytic enantioselective conjugate addition of grignard reagents to cyclic enones using
C
1
-1,1′-bisisoquinoline-based chiral ligands |
| title_fullStr |
Catalytic enantioselective conjugate addition of grignard reagents to cyclic enones using
C
1
-1,1′-bisisoquinoline-based chiral ligands |
| title_full_unstemmed |
Catalytic enantioselective conjugate addition of grignard reagents to cyclic enones using
C
1
-1,1′-bisisoquinoline-based chiral ligands |
| title_sort |
catalytic enantioselective conjugate addition of grignard reagents to cyclic enones using
c
1
-1,1′-bisisoquinoline-based chiral ligands |
| publishDate |
2013 |
| url |
https://hdl.handle.net/10356/96144 http://hdl.handle.net/10220/11770 |
| _version_ |
1681041446234226688 |